Explanation

The Suez Canal is correct because its blockage significantly disrupts major global shipping lanes. The Strait of Malacca is incorrect because while important, the question points to a specific recent event associated with the canal's impact. Indus River is incorrect because it is an inland river and not a primary international trade chokepoint like the others listed. Red Sea is incorrect because although connected, the Suez Canal itself is the more direct answer for major blockage impacts.