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Correct answer: B
Explanation
Ayub A.S is the prophet traditionally associated with a prolonged period of suffering, including skin diseases. Musa A.S's major trial was related to Pharaoh and the commandments. Haroon A.S assisted Musa A.S and did not endure this specific affliction. Essa A.S faced persecution but the duration matching 18 years for skin disease is attributed to Ayub A.S.